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Active site labeling of the Yersinia protein tyrosine phosphatase: The determination of the pKa of the active site cysteine and the function of the conserved histidine 402

โœ Scribed by Zhang, Zhong Yin; Dixon, Jack E.

Book ID
121730716
Publisher
American Chemical Society
Year
1993
Tongue
English
Weight
700 KB
Volume
32
Category
Article
ISSN
0006-2960

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## Abstract Thioredoxin superfamily members share a considerable degree of structural similarity, with a conserved CX~i~X~j~C motif at the active site, where C stand for two cysteines that alternate between a reduced thiol and oxidized disulfide states, and X~i~and X~j~ are two amino acids differen