## Abstract The peroxisome proliferator‐activated receptor‐α (PPAR‐α) plays a key role in lipid metabolism and inflammation. Recently, we demonstrated that administration of the PPAR‐α agonists gemfibrozil and fenofibrate, inhibit the clinical signs of experimental autoimmune encephalomyelitis (EAE
Activators of peroxisome proliferator–activated receptor-α partially inhibit mouse skin tumor promotion
✍ Scribed by Philippe Thuillier; Gaby J. Anchiraico; Kwangok P. Nickel; Regina E. Maldve; Irma Gimenez-Conti; Stephanie J. Muga; Kai-Li Liu; Susan M. Fischer; Martha A. Belury
- Publisher
- John Wiley and Sons
- Year
- 2000
- Tongue
- English
- Weight
- 237 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0899-1987
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract Peroxisome proliferator‐activated receptor‐α (PPARα) is a member of the steroid hormone receptor superfamily. In rodents, PPARα alters genes involved in cell cycle regulation in hepatocytes. Some of these genes are implicated in neuronal cell death. Therefore, in this study, we examined
## Abstract Peroxisome proliferator‐activated receptor gamma (PPAR‐γ) is a member of the nuclear hormone superfamily originally characterized as a regulator of adipocyte differentiation and lipid metabolism. In addition, PPAR‐γ has important immunomodulatory functions. If the effect of PPAR‐γ's act
Enantiomers of a series of substituted analogs of 2-(4-chlorophenoxy) -acetic acid (CPAA) were synthesized and used to examine the influence of steric and structural parameters on peroxisome proliferation. The effects of these compounds were studied on the activation of the peroxisome proliferator-a