The antigen recognized by the DX5 antibody (DX5 antigen) is expressed on all murine NK cells. In the present study we found that a proportion of CD8 + T cells ( ˚5%) also express the DX5 antigen in uninfected mice, and that numbers of CD8 + T cells expressing DX5 are significantly higher in the lung
✦ LIBER ✦
Activation requirements of circulating antigen-specific human CD8+ memory T cells probed with insect cell-based artificial antigen-presenting cells
✍ Scribed by Christian Guelly; Zaruhi Küpcü; Doris Zalusky; Margarete Karner; Margit Zehetner; Tamás Schweighoffer
- Publisher
- John Wiley and Sons
- Year
- 2002
- Tongue
- English
- Weight
- 174 KB
- Volume
- 32
- Category
- Article
- ISSN
- 0014-2980
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## BACKGROUND. Most strategies in cancer immunotherapy are aimed at the induction of a strong cellular immune response against the tumor. Particularly, CD8 + T lymphocytes have been proven in multiple animal models to be critical for the eradication of solid tumors. METHODS. We used a population o