𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Activation of Wnt signaling in cKit-ITD mediated transformation and imatinib sensitivity in acute myeloid leukemia

✍ Scribed by Lara Tickenbrock; Sina Hehn; Bülent Sargin; Georg Evers; Pavankumar Reddy NG; Chunaram Choudhary; Wolfgang E. Berdel; Carsten Müller-Tidow; Hubert Serve


Book ID
107618592
Publisher
Carden Jennings Publishing
Year
2008
Tongue
English
Weight
336 KB
Volume
88
Category
Article
ISSN
0925-5710

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


Epigenetic regulation of signal transduc
✍ Sampa Ghoshal (Gupta); Heinz Baumann; Meir Wetzler 📂 Article 📅 2008 🏛 Elsevier Science 🌐 English ⚖ 350 KB

We have demonstrated that constitutive signal transducer and activator of transcription (STAT) 3 activity, observed in approximately 50% of acute myeloid leukemia (AML) cases, is associated with adverse treatment outcome. Constitutive STAT3 activation may result from the expression of oncogenic prot

PML/RARα fusion protein mediates the uni
✍ Lingna Li; Jie Wang; Richard D. Ye; Guiying Shi; Huifang Jin; Xueming Tang; Jing 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 269 KB

## Abstract Acute promyelocytic leukemia (APL) cells are characterized by PML/RARα fusion protein, high responsiveness to arsenic trioxide (ATO)‐induced cytotoxicity and an abundant generation of reactive oxygen species (ROS). In this study we investigated the association among these three features