𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Activation of vinyl chloride to covalently bound metabolites: roles of 2-chloroethylene oxide and 2-chloroacetaldehyde

✍ Scribed by Guengerich, F. Peter; Crawford, W. Morgan; Watanabe, Philip G.


Book ID
127087736
Publisher
American Chemical Society
Year
1979
Tongue
English
Weight
743 KB
Volume
18
Category
Article
ISSN
0006-2960

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


Mutation induction in chinese hamster V7
✍ Eliezer Huberman; Helmut Bartsch; Leo Sachs 📂 Article 📅 1975 🏛 John Wiley and Sons 🌐 French ⚖ 421 KB

## Abstract Chloroethylene oxide and 2‐chloroacetaldehyde, two possibly carcinogenic metabolites of vinyl chloride in mammals, caused a dose‐dependent induction of 8‐azaguanine‐and ouabain‐resistant mutants in Chinese hamster V79 cells in vitro. Up to one‐hundredfold higher concentrations of 2‐chlo