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Activation of rabbit platelet phospholipase and thromboxane synthesis by 1-o-hexadecyl/octadecyl-2-acetyl-sn-glyceryl-3-phosphorylcholine (platelet activating factor)

✍ Scribed by James O. Shaw; Susan J. Klusick; D.J. Hanahan


Book ID
115738265
Publisher
Elsevier Science
Year
1981
Tongue
English
Weight
627 KB
Volume
663
Category
Article
ISSN
0005-2760

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Phosphono-platelet activating factor I.
✍ Michael C. Moschidis; Constantinos A. Demopoulos; Lena G. Kritikou πŸ“‚ Article πŸ“… 1983 πŸ› Elsevier Science 🌐 English βš– 278 KB

The total synthesis of 1-O-alkyl-2-acetyl-3-glyceryl-(2-trimethyl ammoniummethyl)phosphonate, the phosphono analogue of 1-O-alkyl-2-acetyl-sn-glyceryl-3-phosphorylcho~ne, is described. The phosphonolipid shows much lower activity than the phospholipid stimulating serotonin release from rabbit platel