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Activation of protein kinase C sensitizes the cyclic AMP signalling system of T51B rat liver cells

✍ Scribed by Lise H. Aasheim; Leonard P. Kleine; Douglas J. Franks

Book ID
113388309
Publisher
Elsevier Science
Year
1989
Tongue
English
Weight
686 KB
Volume
1
Category
Article
ISSN
0898-6568

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## Abstract The brief rise in the cellular cyclic AMP content which occurs late in the prereplicative phases of rat hepatocytes in vivo and T51B rat liver epitheloid cells in vitro seems to be necessary for the initiation of DNA synthesis. Thus, the extracellular calcium‐deprivation in T51B rat liv