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Activation of protein kinase C assists insulin producing cells in recovery from raised cytoplasmic Ca2+ by stimulating Ca2+ efflux

✍ Scribed by Per-Olof Berggren; Per Arkhammar; Thomas Nilsson

Book ID: 115761675
Publisher: Elsevier Science
Year: 1989
Tongue: English
Weight: 396 KB
Volume: 165
Category: Article
ISSN: 0006-291X
DOI: 10.1016/0006-291x(89)91086-3

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Activation of protein kinase C has been shown to reduce the Ca 2ϩ responses of a variety of cell types. In most cases, the reduction is due to inhibition of Ca 2ϩ influx, but acceleration of Ca 2ϩ efflux and inhibition of Ca 2ϩ store depletion by protein kinase C activation have also been described.