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Activation of PPARγinhibits K-ras-mediated transformation of intestinal epithelial cells

✍ Scribed by Jinyi Shao; Hongmiao Sheng; Raymond N. Dubois


Book ID
119429163
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
192 KB
Volume
120
Category
Article
ISSN
0016-5085

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Peroxisome proliferator-activated receptor ␥ (PPAR␥) inhibits the growth of several types of cancer cells. However, the mechanisms by which this occurs are poorly understood. The goal of the present study was to investigate the effects of PPAR␥ on mutated ras-induced cell growth, activation of trans