𝔖 Bobbio Scriptorium
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Activation of PPARγ increases PTEN expression in pancreatic cancer cells

✍ Scribed by Buckminster Farrow; B. Mark Evers

Book ID
117053176
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
118 KB
Volume
301
Category
Article
ISSN
0006-291X

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## Abstract Germline mutations in the tumor suppressor gene __PTEN__ (protein phosphatase and tensin homolog located on chromosome ten) predispose to heritable breast cancer. The transcription factor PPARγ has also been implicated as a tumor suppressor pertinent to a range of neoplasias, including