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Activation of phospholipase D in porcine tracheal smooth muscle: role of phosphatidylinositol 3-kinase and RhoA activation

✍ Scribed by Abulkhair M Mamoon; Rodney C Baker; Jerry M Farley

Book ID: 114014368
Publisher: Elsevier Science
Year: 2001
Tongue: English
Weight: 288 KB
Volume: 433
Category: Article
ISSN: 0014-2999
DOI: 10.1016/s0014-2999(01)01439-x

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## Abstract ## Aims To investigate the concentration and activity of RhoA in detrusor and urothelium, as well as the effects of a Rho‐kinase inhibitor, Y‐27632 {(+)‐(R)‐trans‐4‐(1‐aminoethyl)‐N‐(4‐pyridyl) cyclohexanecarboxamide dihydrochloride}, on contraction of the pig urinary bladder. ## Meth