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Involvement of Phosphatidylinositol 3′-Kinase in Stem-Cell-Factor-Induced Phospholipase D Activation and Arachidonic Acid Release

✍ Scribed by Osamu Kozawa; Peter Blume-Jensen; Carl-Henrik Heldin; Lars Rönnstrand


Book ID
115132367
Publisher
John Wiley and Sons
Year
1997
Tongue
English
Weight
791 KB
Volume
248
Category
Article
ISSN
1432-1327

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Involvement of phospholipase D activatio
✍ Osamu Kozawa; Atsushi Suzuki; Junji Shinoda; Nobuaki Ozaki; Yutaka Oiso; Toshihi 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 108 KB 👁 2 views

In a previous study, we have shown that endothelin-1 (ET-1) activates phospholipase D independently from protein kinase C in osteoblast-like MC3T3-E1 cells. It is well recognized that phosphatidylycholine hydrolysis by phospholipase D generates phosphatidic acid, which can be further degraded by pho