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Activation of Phosphatidylinositol-Specific Phospholipase C toward Inositol 1,2-(Cyclic)-Phosphate †

✍ Scribed by Zhou, Chun; Wu, Yiqin; Roberts, Mary F.

Book ID
126215568
Publisher
American Chemical Society
Year
1997
Tongue
English
Weight
206 KB
Volume
36
Category
Article
ISSN
0006-2960

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✍ M.S. Shashidhar; Johannes J. Volwerk; John F.W. Keana; O. Hayes Griffith 📂 Article 📅 1991 🏛 Elsevier Science 🌐 English ⚖ 598 KB

A fluorescent water-soluble substrate for phosphatidylinositol-specific phospholipase C was synthesized. The diacylglycerol moiety of the natural substrate, phosphatidylinositol, was replaced by the fluorescent moiety, 2-naphthol, resulting in the synthetic substrate, racemic 2-naphthyl myo-inositol