Activation of Phosphatidylinositol 3-Kinase by Prolactin in Nb2 Cells
โ Scribed by K.A. Al-Sakkaf; P.R.M. Dobson; B.L. Brown
- Book ID
- 115578410
- Publisher
- Elsevier Science
- Year
- 1996
- Tongue
- English
- Weight
- 256 KB
- Volume
- 221
- Category
- Article
- ISSN
- 0006-291X
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Increase of intracellular cyclic adenosine monophosphate by the permeant cyclic adenosine monophosphate analog, 8-(4-chlorophenylthio)-adenosine 3 H :5 H -cyclic monophosphate, is mitogenic for normal adult rat chromafยฎn cells. The mitogenic effect is blocked by the phosphatidylinositol 3-kinase inh
## Abstract Previously, we showed that retinol inhibited __allโtrans__โretinoic acid (ATRA)โresistant human colon cancer cell invasion via a retinoic acid receptorโindependent mechanism. Because phosphatidylinositol 3โkinase (PI3K) regulates cell invasion, the objective of the current study was to