## Objective: In fibroblasts, transforming growth factor beta (tgf beta) stimulates collagen synthesis and myofibroblast transdifferentiation through the smad intracellular signal transduction pathway. tgf beta-mediated fibroblast activation is the hallmark of scleroderma and related fibrotic condi
Activation of peroxisome proliferator-activated receptor-γ inhibits transforming growth factor-β1 induction of connective tissue growth factor and extracellular matrix in hypertrophic scar fibroblasts in vitro
✍ Scribed by Guo-You Zhang; Tao Cheng; Ming-Hua Zheng; Cheng-Gang Yi; Hua Pan; Zhi-Jie Li; Xing-Long Chen; Qing Yu; Liang-Fu Jiang; Fei-Ya Zhou; Xiao-Yang Li; Jing-Quan Yang; Ting-Gang Chu; Wei-Yang Gao
- Publisher
- Springer-Verlag
- Year
- 2009
- Tongue
- English
- Weight
- 487 KB
- Volume
- 301
- Category
- Article
- ISSN
- 0340-3696
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