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Activation of peripheral κ/δ opioid receptors mediates 15-deoxy-Δ12,14-prostaglandin J2 induced-antinociception in rat temporomandibular joint

✍ Scribed by D.R. Pena-Dos-Santos; F.P. Severino; S.A.L. Pereira; D.B.R. Rodrigues; F.Q. Cunha; S.M. Vieira; M.H. Napimoga; J.T. Clemente-Napimoga

Book ID: 116789030
Publisher: Elsevier Science
Year: 2009
Tongue: English
Weight: 912 KB
Volume: 163
Category: Article
ISSN: 0306-4522
DOI: 10.1016/j.neuroscience.2009.07.052

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## Abstract 15‐deoxy‐Δ^12,14^ prostaglandin J~2~ (15dPGJ~2~), a peroxisome proliferator‐activated receptor gamma (PPARγ) ligand, induced synergistic stimulation of DNA synthesis in the presence of phorbol dibutyrate (PDB) in Swiss 3T3 cells. This effect was dose‐dependent and the maximum response w