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Activation of Notch signal pathway is associated with a poorer prognosis in acute myeloid leukemia

✍ Scribed by Xin Xu; Yu Zhao; Maozhong Xu; Qiuxin Dai; Wenjun Meng; Jiangang Yang; Rujuan Qin

Book ID: 107577282
Publisher: Springer US
Year: 2010
Tongue: English
Weight: 231 KB
Volume: 28
Category: Article
ISSN: 1357-0560
DOI: 10.1007/s12032-010-9667-0

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## Abstract Regulatory T cells (Treg) mediate amelioration of disease and immune homeostasis by inhibiting immune activation and maintaining peripheral immune tolerance. The suppressive mechanisms and clinical significance of Treg have not been completely elucidated in patients with acute myeloid l