Initial blood fetal hemoglobin concentration is elevated and is associated with prognosis in children with acute lymphoid or myeloid leukemia

Elevated frequencies of CD4+CD25+CD127lo

Elevated frequencies of CD4+CD25+CD127lo regulatory T cells is associated to poor prognosis in patients with acute myeloid leukemia

✍ Zhang Shenghui; Han Yixiang; Wu Jianbo; Yu Kang; Bi Laixi; Zhuang Yan; Xu Xi 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 French ⚖ 779 KB

## Abstract Regulatory T cells (Treg) mediate amelioration of disease and immune homeostasis by inhibiting immune activation and maintaining peripheral immune tolerance. The suppressive mechanisms and clinical significance of Treg have not been completely elucidated in patients with acute myeloid l