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Activation of nitrofurantoin to a mutagen by rat liver nitroreductase

✍ Scribed by Herbert S. Rosenkranz; William T. Speck

Book ID
115772904
Publisher
Elsevier Science
Year
1976
Tongue
English
Weight
234 KB
Volume
25
Category
Article
ISSN
0006-2952

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πŸ“œ SIMILAR VOLUMES

Evidence for the existence of a family o
Evidence for the existence of a family of bacterial nitroreductases capable of activating nitrated polycyclics to mutagens
✍ McCoy, Elena C. ;Rosenkranz, Herbert S. ;Mermelstein, Robert πŸ“‚ Article πŸ“… 1981 πŸ› Wiley (John Wiley & Sons) βš– 357 KB

## Abstract A derivative of Salmonella typhimurium TA98 which does not respond to the potent mutagenicity of 1,8‐dinitropyrene is described. This novel strain also shows a lack of response to the mutagenic action of 1,3‐dinitropyrene and a greatly reduced response to 1,6‐dinitropyrene and 1‐nitropy