Activation of mammalian RNA polymerases by polyamines
โ Scribed by D.G.R. Blair
- Book ID
- 107770507
- Publisher
- Elsevier Science
- Year
- 1985
- Tongue
- English
- Weight
- 832 KB
- Volume
- 17
- Category
- Article
- ISSN
- 0020-711X
No coin nor oath required. For personal study only.
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The nuclear run-on transcription assay is the only approach to measure the transcriptional activity of a given gene in its genuine structural and regulatory cellular context. However, serious problems in the interpretation of results can arise from the artificial activation of paused RNA polymerases
## Abstract The introduction of chick erythrocyte nuclei into mammalian cell cytoplasms results in their reactivation as evidenced by the de novo transcription of chick genes and the synthesis of both globin and constitutive proteins. In the present study, chick erythrocytes have been fused to L6 r