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Activation of human T lymphocytes III. Triggering of bystander cytotoxicity in cytotoxic T cell clones by antibodies against the T3 antigen or by a calcium ionophore

โœ Scribed by Hubert Schrezenmeier; Roland Kurrle; Hermann Wagner; Bernhard Fleischer


Publisher
John Wiley and Sons
Year
1985
Tongue
English
Weight
650 KB
Volume
15
Category
Article
ISSN
0014-2980

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Triggering of the lethal hit in human cy
โœ Bernhard Fleischer; Dolores J. Schendel; Dierk Von Steldern ๐Ÿ“‚ Article ๐Ÿ“… 1986 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 624 KB

A monoclonal antibody (CB.l) is described that defines a new triggering signal for human cytotoxic T lymphocytes (CTL). The antibody precipitates a 103-kDa surface antigen from activated normal human T cells. The antigen is undetectable or present in only low amounts on resting T lymphocytes but its