Activation of human B lymphocytes: frequency of antigen-specific B cells triggered by alloreactive or by antigen-specific T cell clones
โ Scribed by Antonio Lanzavecchia; Barbara Parodi; Franco Celada
- Publisher
- John Wiley and Sons
- Year
- 1983
- Tongue
- English
- Weight
- 674 KB
- Volume
- 13
- Category
- Article
- ISSN
- 0014-2980
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๐ SIMILAR VOLUMES
Bovine lymphocyte antigen FACS: Fluorescence-activated cell sorter IL 2: Interleukin 2 mAb: Monoclonal antibody(ies) MHC: Major histocompatibility complex PBMC: Peripheral blood mononuclear cells TCGF: T cell growth factor Tp(M): Theileria parva (Muguga) infected and transformed with TpM sporozoite
Mononuclear cells isolated from human cord blood (CBL) of full-term neonates were stimulated in vitro with a dose range of T cell-dependent antigens, i.e. ovalbumin or sheep erythrocytes, and tested for the capacity to mount an antigen-specific plaque-forming cell (PFC) response. Both of the antigen