Activation of cytotoxic factor production of mouse spleen cells through in-vitro stimulation by lipopolysaccharide and muramyl dipeptide
β Scribed by A. L. Rakhmilevich; M. S. Rakhimova
- Publisher
- Springer US
- Year
- 1988
- Tongue
- English
- Weight
- 333 KB
- Volume
- 105
- Category
- Article
- ISSN
- 0007-4888
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract Spleen cells were collected from normal mice and cultured in a medium containing 20% calf serum. Addition of lipopolysaccharide (LPS) in the culture significantly increased the production of granulocyteβmacrophage colonyβstimulating factor (GMβCSF), and a maximum induction was attained
## Abstract Normal and primed spleen cells stimulated __in vitro__ with sheep RBC showed a different behaviour in the 19 S PFC response. The immunologic capacity of primed cells, unlike that of unprimed cells, was impaired if the antigen addition to culture had been delayed for more than six hours.