✦ LIBER ✦

Activation of caspase-3 and cleavage of Rb are associated with p16-mediated apoptosis in human non-small cell lung cancer cells

✍ Scribed by Katsuda, Koh; Kataoka, Masafumi; Uno, Futoshi; Murakami, Takayoshi; Kondo, Tadashi; Roth, Jack A; Tanaka, Noriaki; Fujiwara, Toshiyoshi

Book ID: 110066479
Publisher: Nature Publishing Group
Year: 2002
Tongue: English
Weight: 225 KB
Volume: 21
Category: Article
ISSN: 0950-9232
DOI: 10.1038/sj.onc.1205272

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Down-regulation of bcl-2 is associated w

Down-regulation of bcl-2 is associated with p16INK4-mediated apoptosis in non-small cell lung cancer cells

✍ Kataoka, M; Wiehle, S; Spitz, F; Schumacher, G; Roth, J A; Cristiano, R J 📂 Article 📅 2000 🏛 Nature Publishing Group 🌐 English ⚖ 209 KB

Inversely correlated expression of p16 a

✍ Masahiro Sakaguchi; Yoshitaka Fujii; Hirohisa Hirabayashi; Hyung-Eun Yoon; Yosuk 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 French ⚖ 469 KB 👁 2 views

Cdk4-mediated phosphorylation of Rb protein is inhibited by pl6, a product of a possible tumor suppressor gene. We examined the expression of p16 and Rb protein by means of immunohistochemistry in 61 non-small cell lung cancers and have demonstrated an inverse relationship between the expression of

ANTIPROLIFERATIVE ACTIVITY OF AUCUBIN IS

ANTIPROLIFERATIVE ACTIVITY OF AUCUBIN IS THROUGH CELL CYCLE ARREST AND APOPTOSIS IN HUMAN NON-SMALL CELL LUNG CANCER A549 CELLS

✍ Jen-Yu Hung; Chih-Jen Yang; Ying-Ming Tsai; Hurng-Wern Huang; Ming-Shyan Huang 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 351 KB

Ectopic expression of herpes simplex vir

Ectopic expression of herpes simplex virus-thymidine kinase gene in human non-small cell lung cancer cells conferred caspase-activated apoptosis sensitized by ganciclovir

✍ Chien-Chih Chiu; Yuan-Lin Kang; Tsung-Hsiang Yang; Chih-Hsin Huang; Kang Fang 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 French ⚖ 689 KB

Human non-small cell lung cancer (NSCLC) cells were transfected with recombinant prodrug herpes simplex virus type I thymidine kinase (HSV-tk) cDNA, and the selected clones underwent apoptosis in response to induction by antiviral ganciclovir (GCV). The efficiency of GCV-induced growth inhibition an

Induction of tubulin by docetaxel is ass

Induction of tubulin by docetaxel is associated with p53 status in human non small cell lung cancer cell lines

✍ Jinghua Tsai Chang; Gee-Chen Chang; Jiunn-Liang Ko; Hung-Ya Liao; Hsin-Ju Liu; C 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 French ⚖ 408 KB 👁 1 views

Docetaxel (DOC), a member of the taxane family of anticancer drugs, binds to tubulin and produces unnaturally stable microtubules that induce cell death. DOC is used clinically alone or in combination with other compounds to treat advanced stages of cancer. We have treated the human lung cancer cell

Association of smoking with apoptosis-re

Association of smoking with apoptosis-regulated proteins (Bcl-2, Bax and p53) in resected non-small-cell lung cancers

✍ Takaomi Hanaoka; Jun Nakayama; Jun Mukai; Shinji Irie; Takeshi Yamanda; Taka-Aki 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 French ⚖ 42 KB 👁 2 views

FIGURE 1 -Survival after surgery of patients with NSCLC according to p53 expression level. Log-rank tests used for comparisons.