Activation of an enzyme simulated by explicit dynamics of an active site lid
β Scribed by Northrup, S.H.
- Book ID
- 119410727
- Publisher
- Biophysical Society
- Year
- 1996
- Tongue
- English
- Weight
- 119 KB
- Volume
- 71
- Category
- Article
- ISSN
- 0006-3495
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π SIMILAR VOLUMES
The possibility that fluctuations of electric field strength (electrostatic fluctuations) in an enzyme active site are a source of reaction activation has been considered within the framework of a simple one-dimensional quantum model of reaction rates. The electric field is treated as a classical pe
Aspartate β€-semialdehyde dehydrogenase ASADH is an important enzyme in the synthesis of essential amino acids and therefore an attractive target for antibacterial, fungicidal, or herbicidal agents. The structure of the enzyme has recently Ε½ . been determined by X-ray crystallography Hadfield et al.,