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Activation by glutathione: A possible contribution to the mutagenicity of patulin

✍ Scribed by Carolin Pfenning; Leane Lehmann


Book ID
116925369
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
85 KB
Volume
211
Category
Article
ISSN
0378-4274

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The mutagenicity of tetrachloroethene (tetra) and its S conjugate, S-(1,2,2-trichlorovinyl)glutathione (TCVG) was investigated using a modified Ames preincubation assay. TCVG was a potent mutagen in presence of rat kidney particulate fractions containing high concentrations of y-glutamyl transpeptid