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Activation and translocation of PKCδ is necessary for VEGF-induced ERK activation through KDR in HEK293T cells

✍ Scribed by Masamitsu Kuriyama; Taizo Taniguchi; Yasuhito Shirai; Atsuo Sasaki; Akihiko Yoshimura; Naoaki Saito

Book ID
116289451
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
741 KB
Volume
325
Category
Article
ISSN
0006-291X

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## Abstract We examined the signalling pathways responsible for the Ang II induction of growth in MCF‐7 human breast cancer cells. Ang II in MCF‐7 cells induced: (a) the translocation from the cytosol to membrane and nucleus of atypical protein kinase C‐ζ (PKC‐ζ) but not of PKC‐α, ‐δ, ‐ε and ‐η; (b