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Activation and inhibition of the erythropoietin receptor by a membrane-anchored erythropoietin

โœ Scribed by Olivier Negre; Floriane Fusil; Annie Henri; Jean-Marie Villette; Philippe Leboulch; Yves Beuzard; Emmanuel Payen


Book ID
113616437
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
978 KB
Volume
36
Category
Article
ISSN
0301-472X

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A partial model of the erythropoietin re
โœ Caravella, Justin A.; Lyne, Paul D.; Richards, W. Graham ๐Ÿ“‚ Article ๐Ÿ“… 1996 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 836 KB

A model of the structure of erythropoietin (Epo) is presented based on structural homology to other hemopoietic cytokines. A model of the erythropoietin receptor complex w a s made based on evidence that this includes a homodimer of the receptor chain with known sequence. Key interactions are noted