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Activated T lymphocytes, rheumatoid factor and erythrocyte sedimentation rate assays in rheumatoid arthritis

✍ Scribed by H. Bartfeld; C. Dham

Book ID
104696204
Publisher
Springer
Year
1988
Tongue
English
Weight
269 KB
Volume
8
Category
Article
ISSN
0172-8172

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✦ Synopsis

Activated T lymphocytes (Ia+ T-cells) in peripheral blood are associated with immune stimulation. We found the percentages of these cells significantly increased in 95% of rheumatoid arthritis (RA) patients. Our studies showed no relation between the percentages of these cells in peripheral blood and concurrent erythrocyte sedimentation rates or rheumatoid factor titers. Circulating immune complex titers determined in a small number of patients conjectured an association with Ia+ T-cell levels.

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## Abstract The characteristics of circulating blood lymphocytes in 16 patients with rheumatoid arthritis (RA) on cyclophosphamide (CPA) were compared with 49 control RA patients and 70 normal volunteers. In all three groups the percentages of B‐ and T‐lymphocytes were the same. In untreated RA the