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Activated protein C in sepsis: down but not out, yet

✍ Scribed by Ritesh Agarwal,Alok Nath

Book ID
126388029
Publisher
Springer (Biomed Central Ltd.)
Year
2006
Tongue
English
Weight
30 KB
Volume
10
Category
Article
ISSN
1466-609X

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The role of lysines 37-39 (chymotrypsin numbering) in the 37-loop of the serine protease activated protein C (APC) was studied by expressing acidic and neutral recombinant APC (rAPC) mutants. Activity of the APC mutants was assessed using human plasma and plasma-purified and recombinant derivatives