Activated Antibiotic Production by Inducing Resistance to Capreomycin in Streptomyces lividans and Streptomyces coelicolor
β Scribed by Qin ZHANG; Bao-Quan ZHU; Hai-Feng HU
- Book ID
- 119639222
- Publisher
- Elsevier
- Year
- 2008
- Tongue
- Chinese
- Weight
- 340 KB
- Volume
- 6
- Category
- Article
- ISSN
- 1875-5364
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
A single gene from Streptomyces tenjimariensis, conferring resistance to kanamycin, apramycin and sisomicin, has been cloned in Streptomyces lividans. The mechanism of resistance involves methylation of 16S RNA in the 30S ribosomal subunit.
The continuous production of a hybrid antibiotic by a transformed strain of Streptomyces lividans TK21 in a three-phase fluidized bed is studied. Cell aggregates, known as pellets, are used as immobilized cell particles in the bioreactor. A methodology to prepare pellets of a suitable size and morph