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Action of dimethindene on the electrophysiological and mechanical properties of atrial and ventricular myocardium of guinea-pig

✍ Scribed by János Mészáros; József Szegi

Book ID
115878082
Publisher
Elsevier Science
Year
1983
Tongue
English
Weight
509 KB
Volume
96
Category
Article
ISSN
0014-2999

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The electrophysiological effects of urapidil, a new aradrenoceptor antagonist, were assessed in the reserpinized guinea-pig ventricular myocardium. Urapidil suppressed the maximal rate of rise (Vm~) of steady-state action potentials elicited by the fast responses at high concentrations independently