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Actin Cytoskeleton as a Target for 2-Chloro Adenosine: Evidence for Induction of Apoptosis in C2C12 Myoblastic Cells

✍ Scribed by Stefano Rufini; Gabriella Rainaldi; Maria Pia Abbracchio; Carla Fiorentini; Miriam Capri; Claudio Franceschi; Walter Malorni


Book ID
115580855
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
941 KB
Volume
238
Category
Article
ISSN
0006-291X

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## Abstract We previously demonstrated that both Cladribine (2‐chloro‐deoxyadenosine) and the related compound 2‐chloroadenosine induce apoptosis of human astrocytoma cells (Ceruti et al. [2000] J Neurosci Res 60:388–400). In the present study we have characterized the role of the most important β€œe