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Evidence for a resident subset of cells with SP phenotype in the C2C12 myogenic line: a tool to explore muscle stem cell biology

✍ Scribed by Rachid Benchaouir; Philippe Rameau; Charles Decraene; Patrick Dreyfus; David Israeli; Geneviève Piétu; Olivier Danos; Luis Garcia

Book ID: 116980878
Publisher: Elsevier Science
Year: 2004
Tongue: English
Weight: 734 KB
Volume: 294
Category: Article
ISSN: 0014-4827
DOI: 10.1016/j.yexcr.2003.11.005

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FGF6 mediated expansion of a resident subset of cells with SP phenotype in the C2C12 myogenic line

✍ David Israeli; Rachid Benchaouir; Simindokht Ziaei; Philippe Rameau; Carole Grus 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 567 KB

## Abstract Fibroblast growth factor 6 (FGF6) is selectively expressed during muscle development and regeneration. We examined its effect on muscle precursor cells (mpc) by forcing stable FGF6 expression in C2C12 cells in vitro. FGF6 produced in genetically engineered mpc was active, inducing stron