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Acridone-Based Inhibitors of Inosine 5‘-Monophosphate Dehydrogenase: Discovery and SAR Leading to the Identification of N -(2-(6-(4-Ethylpiperazin-1-yl)pyridin-3-yl)propan-2-yl)-2- fluoro-9-oxo-9,10-dihydroacridine-3-carboxamide (BMS-566419)

✍ Scribed by Watterson, Scott H.; Chen, Ping; Zhao, Yufen; Gu, Henry H.; Dhar, T. G. Murali; Xiao, Zili; Ballentine, Shelley K.; Shen, Zhongqi; Fleener, Catherine A.; Rouleau, Katherine A.; Obermeier, Mary; Yang, Zheng; McIntyre, Kim W.; Shuster, David J.; Witmer, Mark; Dambach, Donna; Chao, Sam; Mathur, Arvind; Chen, Bang-Chi; Barrish, Joel C.; Robl, Jeffrey A.; Townsend, Robert; Iwanowicz, Edwin J.

Book ID: 118178549
Publisher: American Chemical Society
Year: 2007
Tongue: English
Weight: 206 KB
Volume: 50
Category: Article
ISSN: 0022-2623
DOI: 10.1021/jm070299x

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