✦ LIBER ✦

Acquisition and use of calorimetric data for prediction of the thermodynamics of ligand-binding and folding reactions of proteins

✍ Scribed by Patrick R Connelly

Publisher: Elsevier Science
Year: 1994
Tongue: English
Weight: 1015 KB
Volume: 5
Category: Article
ISSN: 0958-1669
DOI: 10.1016/0958-1669(94)90046-9

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Use of the Macintosh computer for data a

Use of the Macintosh computer for data acquisition

✍ W. L. Baun 📂 Article 📅 1988 🏛 John Wiley and Sons 🌐 English ⚖ 663 KB

Structure prediction and fold recognitio

Structure prediction and fold recognition for the ferrochelatase family of proteins

✍ M. Hansson; S.P. Gough; S.S. Brody 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 214 KB 👁 2 views

An alpha/beta barrel is predicted for the three-dimensional (3D) structure of Bacillus subtilis ferrochelatase. To arrive at this structure, the THREADER program was used to find possible homologous 3D structures and to predict the secondary structure for the ferrochelatase sequence. The secondary s

Prediction of the binding energy for sma

Prediction of the binding energy for small molecules, peptides and proteins

✍ Matthieu Schapira; Maxim Totrov; Ruben Abagyan 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 262 KB 👁 1 views

A fast and reliable evaluation of the binding energy from a single conformation of a molecular complex is an important practical task. Knowledge-based scoring schemes may not be sufficiently general and transferable, while molecular dynamics or Monte Carlo calculations with explicit solvent are too

Interactions of drugs with proteins II:

Interactions of drugs with proteins II: Experimental methods, treatment of experimental data, and thermodynamics of binding reactions of thymoleptic drugs and model dyes

✍ H. J. Weder; M. H. Bickel 📂 Article 📅 1970 🏛 John Wiley and Sons 🌐 English ⚖ 774 KB

Predicted structure and fold recognition

Predicted structure and fold recognition for the glutamyl tRNA reductase family of proteins

✍ S.S. Brody; S.P. Gough; C.G. Kannangara 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 556 KB

The conserved residues of glutamyl tRNA reductase (GTR) from Hordeum vulgare (GTRhorvu) were found from an alignment/pile-up of 24 homologous sequences found using BLAST searches. A multiple alignment of sequences was used to obtain a prediction of the secondary structure of the GTR's. This secondar

New and fast statistical-thermodynamic m

New and fast statistical-thermodynamic method for computation of protein-ligand binding entropy substantially improves docking accuracy

✍ A. M. Ruvinsky; A. V. Kozintsev 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 101 KB 👁 1 views

## Abstract We present a novel method to estimate the contributions of translational and rotational entropy to protein‐ligand binding affinity. The method is based on estimates of the configurational integral through the sizes of clusters obtained from multiple docking positions. Cluster sizes are