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Acquired expression of transcriptionally active p73 in hepatocellular carcinoma cells

โœ Scribed by Sayan, A Emre; Sayan, Berna S; Findikli, Necati; Ozturk, Mehmet

Book ID
110065921
Publisher
Nature Publishing Group
Year
2001
Tongue
English
Weight
254 KB
Volume
20
Category
Article
ISSN
0950-9232

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p73 Is up-regulated in a subset of hepat
p73 Is up-regulated in a subset of hepatocellular carcinomas
โœ Nirmitha I. Herath; Michael C. Kew; Vicki L. Whitehall; Michael D. Walsh; Jeremy ๐Ÿ“‚ Article ๐Ÿ“… 2000 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 204 KB

Loss of heterozygosity (LOH) at 1p36 occurs in a number of solid tumors including hepatocellular carcinoma (HCC). Recently, a novel gene, p73, has been identified at 1p36.33. p73 is structurally and functionally related to p53 located at 17p13.1, which is a target for inactivation in HCCs. p73 produ