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Acidic Fibroblast Growth Factor Enhances Peroxynitrite-Induced Apoptosis in Primary Murine Fibroblasts

✍ Scribed by Jordan T. Shin; Luis Barbeito; Lee Ann Macmillan-Crow; Joseph S. Beckman; John A. Thompson


Book ID
115566304
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
529 KB
Volume
335
Category
Article
ISSN
0003-9861

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In this study, we investigate the effects of bFGF on apoptosis in neuron-free cultures of neonatal rat Schwann cells. Apoptotic cell death was induced in primary and secondary expanded Schwann cells by treatment with 1 mM concentrations of 8-bromoadenosine 38:58-cyclic monophosphate (8-bromo-cAMP),