Down-regulation of FLIP sensitizes rheum
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Guillermo Palao; BegoΓ±a Santiago; MarΓa Galindo; MΓ³nica PayΓ‘; Juan C. Ramirez; J
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Article
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2004
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John Wiley and Sons
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English
β 238 KB
## Abstract ## Objective Hyperplasia of fibroblastβlike synoviocytes (FLS) contributes to chronic inflammation and joint destruction in rheumatoid arthritis (RA). FLICEβinhibitory protein (FLIP) is an antiapoptotic protein that might prevent apoptotic elimination of FLS in response to death ligand