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Characterization of Apt- cell lines exhibiting cross-resistance to glucocorticoid- and Fas-mediated apoptosis

✍ Scribed by Askew, David J; Kuscuoglu, Unsal; Brunner, Thomas; Green, Douglas R; Miesfeld, Roger L


Book ID
110015948
Publisher
Nature Publishing Group
Year
1999
Tongue
English
Weight
767 KB
Volume
6
Category
Article
ISSN
1350-9047

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## Abstract Our study was conducted to investigate whether anticancer drugs, cisplatin (CDDP) and/or 5‐fluorouracil (5‐FU), can modulate Fas‐mediated apoptosis in oral squamous cell carcinoma (OSCC) cell lines. When OSCC cell lines, NA and HSC‐4, were treated with CDDP and/or 5‐FU, Fas and its mRNA