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Acid phosphatase activity of promastigotes of Leishmania donovani: a marker of virulence

✍ Scribed by Neena Singla; G.K. Khuller; V.K. Vinayak


Book ID
109317665
Publisher
John Wiley and Sons
Year
1992
Tongue
English
Weight
276 KB
Volume
94
Category
Article
ISSN
0378-1097

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For the presentation of Leishmania promastigotes to polyclonal CD4+ Tcells, a processing period within activated macrophages of 3-4 h is required. Presentation can be inhibited by both chloroquine and brefeldin A (BFA), the latter implicating a requirement for newly synthesized MHC class I1 molecule