๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Acid-induced transient isotachophoretic stacking of basic drugs in co-electroosmotic flow capillary zone electrophoresis

โœ Scribed by Joselito P. Quirino; Michael C. Breadmore

Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
591 KB
Volume
35
Category
Article
ISSN
1615-9306

No coin nor oath required. For personal study only.

โœฆ Synopsis

Abstract

Online sample concentration or stacking of basic drugs by transient isotachophoresis with the injection of an acid in coโ€electroosmotic flow capillary zone electrophoresis was studied experimentally and with computer simulation. The acid stacking strategy afforded an order of magnitude improvement in concentration sensitivity for model tricyclic antidepressant and ฮฒ blocker drugs.

๐Ÿ“œ SIMILAR VOLUMES

Base-induced transient isotachophoretic
Base-induced transient isotachophoretic stacking of acidic drugs in capillary zone electrophoresis
โœ Joselito P. Quirino ๐Ÿ“‚ Article ๐Ÿ“… 2011 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 435 KB

## Abstract Online sample concentration of acidic drugs by transient isotachophoresis (tโ€ITP) with the injection of a base is described in capillary zone electrophoresis (CZE). A positively coated capillary was conditioned with background electrolyte (ammonium acetate at pH 6). A long plug of sampl

Novel approach for the rapid determinati
Novel approach for the rapid determination of water-soluble organic acids in wine by co-electroosmotic flow capillary zone electrophoresis
โœ Federica Bianchi; Maria Careri; Claudio Corradini ๐Ÿ“‚ Article ๐Ÿ“… 2005 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 467 KB ๐Ÿ‘ 1 views

## Abstract An innovative protocol for the fast analysis of some organic acids in red wine by coโ€electroosmotic capillary zone electrophoresis and indirect UV detection using hexadimethrine bromide (HDB) as coating agent was proposed. The adsorption of HDB onto the capillary wall provided a stable