Acid-catalyzed rearrangements of 4-carboxy-5-(2′-hydroxyphenyl) prolines
✍ Scribed by Yu. N. Belokon'; N. G. Faleev; V. M. Belikov; V. A. Maksakov; P. V. Petrovskii
- Book ID
- 112447851
- Publisher
- Springer
- Year
- 1977
- Tongue
- English
- Weight
- 314 KB
- Volume
- 26
- Category
- Article
- ISSN
- 1573-9171
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📜 SIMILAR VOLUMES
The Cope rearrangement of 1,5-dienes bearing acyl substituents in the 2-position of the diene system is strongly accelerated by protic and Lewis acids. Table 1. Rearrangement of 2-Acyl-1,5-dienes. Starting Material Acid Mol % Acid Conditionsa Productsb Isolated Yield !A CF3C02H 100 15 min, CH2C12 ,&
The acid-catalyzed rearrangements of three model tricyclo[4.3.2] propellane derivatives have been explored. In each case the observed products are proposed to arise via a concerted 1,2-shift of the cyclobutane bond having an antiperiplanar alignment with the leaving group (i.e., stereoelectronic con