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Acid-catalysed transformation of ?-trifluoromethanesulfonates of ?- and ?-lactones into 2,5-disubstituted homochiral tetrahydrofurans

โœ Scribed by Wheatley, Joseph R.; Bichard, Claire J. F.; Mantell, Simon J.; Son, Jong Chan; Hughes, David J.; Fleet, George W. J.; Brown, David


Book ID
124060096
Publisher
The Royal Society of Chemistry
Year
1993
Tongue
English
Weight
283 KB
Volume
13
Category
Article
ISSN
0022-4936

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A convenient synthesis of 3-functionaliz
โœ Vladimir I. Tyvorskii; Alexander S. Kukharev; Oleg G. Kulinkovich; Norbert De Ki ๐Ÿ“‚ Article ๐Ÿ“… 1998 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 422 KB

A convenient procedure for the preparation of 3-functionalized 5-aikoxymethyl-and 5phenoxymethyl-2(SH)-furanones is described. The method is basedonthe condensation of various p-alkoxy-or ~-phenoxy-a-hydroxy ketones with ~activated esters in the presence of catalytic amounts of sodium methoxide. Res