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A convenient synthesis of 3-functionalized 5-alkoxymethyl- and 5-phenoxymethyl-2(5H)-furanones and their transformations into related epoxy and methylene lactones

✍ Scribed by Vladimir I. Tyvorskii; Alexander S. Kukharev; Oleg G. Kulinkovich; Norbert De Kimpe; Kourosch Abbaspour Tehrani


Book ID
104208304
Publisher
Elsevier Science
Year
1998
Tongue
French
Weight
422 KB
Volume
54
Category
Article
ISSN
0040-4020

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✦ Synopsis


A convenient procedure for the preparation of 3-functionalized 5-aikoxymethyl-and 5phenoxymethyl-2(SH)-furanones is described. The method is basedonthe condensation of various p-alkoxy-or ~-phenoxy-a-hydroxy ketones with ~activated esters in the presence of catalytic amounts of sodium methoxide. Results are reported showing the possible transformations of these 2(5H)furanones into related epoxy and a-methylene laetones.


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