𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Acetyldiaminobutanoic acid, a potential lathyrogenic amino acid in leaves of Acacia angustissima

✍ Scribed by Jess D Reed; Girma Gebre-Mariam; Christopher J Robinson; Jean Hanson; Agnes Odenyo; Paul M Treichel

Publisher
John Wiley and Sons
Year
2001
Tongue
English
Weight
105 KB
Volume
81
Category
Article
ISSN
0022-5142

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

Acacia angustissima has potential in agroforestry systems for forage production in tropical environments. However, feeding trials indicate that the leaves are potentially toxic. Signs of toxicity in sheep are similar to those presented by sheep fed flatpea (Lathyrus sylvestris) hay which contains a high concentration of the non‐protein amino acid 2,4‐diaminobutanoic acid (DABA). Cation exchange chromatography, high‐performance liquid chromatography (HPLC) and NMR were used to isolate and identify the non‐protein amino acid in A angustissima leaves. A quantitative HPLC method was used to determine the content of the non‐protein amino acid in leaves from 20 accessions. The non‐protein amino acid was identified as 4‐N‐acetyl‐2,4‐diaminobutanoic acid (ADAB), previously reported to occur in seeds. The average and range in ADAB content were 16.8 and 10.6–25.4 mg g^−1^ respectively. This content of ADAB is higher than the levels of DABA in flatpea hay that are toxic to sheep.

© 2001 Society of Chemical Industry

📜 SIMILAR VOLUMES

Cysteine: A potential source of error in
Cysteine: A potential source of error in amino acid analysis of mercaptoethane sulfonic or hydrochloric acid hydrolysates of proteins and peptides
✍ Michael L.G. Gardner 📂 Article 📅 1984 🏛 Elsevier Science 🌐 English ⚖ 231 KB

Hydrolysis of proteins and peptides with mercaptoethane sulfonic acid is liable to produce overestimation of the proline content owing to the production of ninhydrin-positive material (probably cysteine) which coelutes with proline on many ion-exchange analytical systems. A similar error occurs with

Effect of amino acids containing sulfur
Effect of amino acids containing sulfur on the corrosion of mild steel in phosphoric acid solutions polluted with Cl−, F− and Fe3+ ions–behaviour near and at the corrosion potential
✍ Mohamed Samir S Morad; Abo El-Hagag A Hermas; Mohamed S Abdel Aal 📂 Article 📅 2002 🏛 Wiley (John Wiley & Sons) 🌐 English ⚖ 167 KB 👁 2 views

## Abstract Research on non‐toxic inhibitors is of considerable interest in investigations into the replacement of hazardous classical molecules. This paper reports the action of four amino acids containing sulfur on the corrosion of mild steel in phosphoric acid solution with and without Cl^−^, F^