Acetylation with acetic-1–13-C pivalic anhydride

✍ Scribed by Walter J. Horton; Steven P. Adams; Mary W. Niermeyer

• Book ID: 102369991
• Publisher: John Wiley and Sons
• Year: 1977
• Tongue: French
• Weight: 285 KB
• Volume: 13
• Category: Article
• ISSN: 0022-2135
• DOI: 10.1002/jlcr.2580130420

✦ Synopsis

Abstract

In situ formation of acetic‐1–^13^‐C pivalic anhydride constitutes a convenient and economical means of preparing C‐13 containing acetanilides in excellent yield. Similarly, in situ formation of pivalic anhydride yields pivanilides. An elegant synthesis of p‐acetylaminobenzaldehyde from p‐nitro‐benzaldehyde via the acetal is described.