ACETYLATION OF 2-AMINO-2-OXAZOLINES: EVIDENCE OF A RING CLEAVED ACETYLATED COMPOUND

✍ Scribed by Forfar, Isabelle; Jarry, Christian; Leger, Jean-Michel

• Book ID: 120837117
• Publisher: Walter de Gruyter GmbH & Co. KG
• Year: 1997
• Tongue: English
• Weight: 361 KB
• Volume: 3
• Category: Article
• ISSN: 0793-0283
• DOI: 10.1515/HC.1997.3.5.473

✦ Synopsis

Depending on the experimental conditions the reaction of 5-substituted 2-amino-2-oxazolines 1 with acetic anhydridee led to acetylated compounds which exhibit or not an heterocyclic ring. The 5substituted 3-acetyl-2-oxazolidinones 4 were finally isolated in boiling acetic anhydride. Vol 3. No. 5, 1997 Acetylation of 2-Amino-2-Oxazolines: Evidence of a Ring Cleaved Acetylated Compound 0-N acyl migration < 10 ). The transient formation of 2 was always suggested by tic during the described acetylation procedures. Scheme 1 RCH 2 NHCOCHN OCONHCOCH3 2 (a,b) ACJO o°c r -Ν 0 Λ-ΝΗ 2 1 (a,b) RC -Ν 0 Λ-ΝΗ 2 1 (a,b)