Decarboxylative acylation of thiolmalona
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Yoshiaki Kobuke; Jun-ichi Yoshida
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Article
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1978
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Elsevier Science
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French
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In the biosynthesis of fatty acids and polyketides, 1 the malonyl group attached to one of the two sulfhydryl groups (so called "central" SH-group) in the multienzyme complex is decarboxylatively acylated by the acetyl residue attached to the other ("peripheral" SH-group), giving rise to acetothiol