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Acetoxy-4-methylcoumarins confer differential protection from aflatoxin B1-induced micronuclei and apoptosis in lung and bone marrow cells

โœ Scribed by Hanumantharao G Raj; Ekta Kohli; Vishwajeet Rohil; B.S Dwarakanath; Virinder S Parmar; Smita Malik; J.S Adhikari; Yogesh K Tyagi; Sanjay Goel; Kshitij Gupta; Mridula Bose; Carl E Olsen

Book ID
117766725
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
145 KB
Volume
494
Category
Article
ISSN
1383-5718

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Aflatoxin B1-induced micronuclei and cel
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โœ Hanumantharao G. Raj; Kshitij Gupta; Viswajeet Rohil; Mridula Bose; Gopa Biswas; ๐Ÿ“‚ Article ๐Ÿ“… 1998 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 264 KB

Aflatoxin B 1 (AFB 1 ) is a clastogen that causes cellular damage by covalent modification of nucleic acids. In this investigation, male rats were injected i.p. with AFB 1 (8 mg/kg b.w.) in DMSO and the same dose of AFB 1 was also administered intratracheally (i.t.) to the animals separately. The an